APPLICATION OF INDIVIDUAL LY TESTED DOSES NYSTATIN IN TREATMENT OF PATIENTS WITH INTESTINAL CANDIDIASIS
N.E. Djumaeva. Research Institute for Epidemiology, Microbiology and Infectious Diseases , Tashkent, Uzbekistan
To test the individual daily dose of poliene antimycotic Nystatinum ( Mycostatinum) for patients with intestinal candidiasis we used non- invasive express – method of testing daily dose of drugs. The method is based on registration of bio- potentials on acupuncture sites of the organs under study. All patients signed fully informed consent to be involved into the study. The patients with the verified diagnosis of intestinal candidiasis (fungal disbacteriosis) composed the main group ( 15(60%) and the control group (10(40%) . have been studied by microscopically, cultural and endoscope methods from January 2003 to February 2004. The age range from 15 to 61 (median 38).The sex ratio (M\ F) – 1,3( 11\14).The doses of Nystatinum were individually tested by Mini- Expert DT (Russia) at different stages of the therapy. The patients of the control group were treated by routine doses of Nystatinum ( 6 000 000 Un per day during 10 days).
In the main group , the individual tested doses of Nystatinum ranged from 4 500 000 Un to 13 500 000 Un , while the 13 – days course doses ranged from 28 500 000 un to 78 750 000 Un administered as bolus- therapy. After the treatment the signs of clinical and etiological recovery were registered in 14( 93,5%) patients of the main group and in 3 (30%) patients of the control group.
There were no complications or adverse effects of application of Nystatinum in the individually tested doses. Comparison of these findings shows that Nystatinum is a drug of choice when treating intestinal candidiasis , it being recommended to use according to the results of individual testing doses as this has an evident curative effect.
Published in 8th World Conference on Clinical Pharmacology & Therapeutics, Australia, Brisbon.Vol.31, Supp.1, pp 114-115, August 2004.
MD,PhD(candidate of the medical sciences), Neurologist of higher category
e-mail : | dr_djumaeva@hotmail.com |
“this scientific work is relevant to very important problem of resonance geometry of processes of individual life activity and condition of his health and disease” Academician of Russian Academy of Medical Science, professor V.P.Kaznacheev